Boneset comes from Eupatorium perfoliatum, a perennial herb native to North America. Herbalists prepare the aerial parts as teas, tinctures, or extracts. The plant has a long history of traditional use.
People often take boneset in small, frequent doses at the first sign of symptoms. Its traditional role is to ease the discomfort of fever, colds, and flu and to support healthy immune function.
**Key cautions:** Boneset contains pyrrolizidine alkaloids (PAs). These compounds can harm the liver if you take large amounts or use the herb for a long time. Avoid boneset if you are pregnant or breastfeeding. Talk to a professional about safe dosing and duration.