Mangosteen (Garcinia mangostana) is a tropical fruit. Its thick, purple rind contains compounds called xanthones, which give the fruit antioxidant activity. Supplements are sold as juice, whole-fruit powder, or standardized extract.
Take mangosteen for antioxidant support and general well-being. It can be taken at any time, as juice or capsules. Human research on its specific effects is limited, with evidence largely from lab and animal studies.
Avoid concentrated extracts if pregnant or breastfeeding because safety data are lacking. Animal and lab data hint that mangosteen could slow blood clotting, so talk to your doctor if you take warfarin or similar drugs. It might also lower blood sugar, so monitor closely if you use diabetes medicine. These interactions are not well proven in people.