Octodrine (also called DMHA) is a synthetic stimulant related to phenethylamine. Manufacturers add it to some pre-workout and weight-loss products for a perceived boost in energy, focus, and performance. Because sound safety and efficacy data are scarce, mainstream authorities have not endorsed these uses.
People typically swallow a capsule or mix a powder 30 minutes before training. Octodrine can strain the cardiovascular system. Elevated heart rate, rising blood pressure, and interactions with other stimulants are real concerns. Habitual use may also lead to dependence.
Anyone with a heart condition, high blood pressure, or who is pregnant or nursing should avoid it.