Oils, nuts, and seeds contain stigmasterol, a plant sterol. Supplement makers blend it with other phytosterols. These blends help reduce the amount of dietary cholesterol your body absorbs.
Most research on cholesterol support used mixed phytosterol blends, not isolated stigmasterol. Take the supplement with a fat-containing meal to improve absorption. These products do not replace prescribed medications.
Plant sterols can lower uptake of fat-soluble vitamins A, D, E, and K. People with sitosterolemia should avoid all plant sterol supplements.